Subsections
[Cr:4, Lc:1, Tt:0, Lb:9]
- Analysis of organic binary mixtures: Separation and identification of
organic binary mixtures containing substituents. (A student is
expected to analyze atleast 8-10 different binary mixtures). Chemical
reactions and derivatisations.
- Synthesis and purification of organic compounds involving one and
two/three stages: Reactions involving nitration, halogenation,
oxidation, reduction, alkylation/acylation, condensation,
esterification and rearrangement etc will be covered. Examples will be
selected from:
- Preparation of benzydrol from benzophenone.
- Prepration of menthone from menthol.
- Preparation of dibenzylideneacetone.
- Nitration of methyl benzoate to prepare methyl-3-nitrobenzoate.
- Benzoylation of bromobenzene to prepare 4-bromobenzophenone.
- Preparation of 2-aminobenzoic acid from phthalimide.
- Preparation of trans-stilbene from benzyl halide and
benzaldehyde.
- Preparation of p-bromoaniline from aniline.
- Preparation of trans-cyclohexane-1,2-diol from cyclohexene.
- Preparation of E-3-phenylpropenoic acid (cinnamic acid) followed by
esterification from benzaldehyde and malonic aicd.
- Preparation of paracetamol.
- Coumarine synthesis.
- Extraction of caffeine from tea.
- Extraction of nicotine from cigarettes.
- L. M. Harwood, C. J. Moody, J. M. Percy, Experimental Organic
Chemistry, 2nd Ed, Blackwell Science, Oxford (1999).
- B. S. Furniss, A. J. Hannaford, P. W. G. Smith, A. R. Tatchell,
Vogel's Textbook of Practical Organic Chemistry, Indian
Edition, 5th Ed, Pearson Education, New Delhi (2008).
- J. S. Nimitz, Experiments in Organic Chemistry: From Microscale
to Macroscale, Prentice Hall, New Jersey (1990).
- F. G. Mann, B. C. Saunders, Practical Organic Chemistry, Indian
Edition, 4th Ed, Orient Longman, Noida (2007).
