Subsections
[Cr:4, Lc:3, Tt:0, Lb:0]
- Selectivity in organic reactions: Chemoselectivity, regioselectivity,
enantio- and stereo-selectivity. Stereoaspects of the addition of
X
, HX, boranes and hydroxylation to C=C
systems. Cis- and trans-hydroxylation of cycloalkenes.
Atropisomerism. Racemisation, resolution, prostereoisomerism,
stereotopicity and enantiomeric excess. Chirality-optical isomerism in
biphenyls, allenes. Geometrical isomerism-acylic and cyclic compounds.
- Selected named reactions: Aldol, Arndt-Eistert, Bardhan-Sengupta,
Baker-Venkataraman, Barbier, Barton, Baylis-Hillman, Benzoin, Birch,
Cannizaro, Corey-Bakshi-Shibata, Corey-Seebach, Darzen, Dakin,
Diels-Alder, Dieckmann, Fischer, Friedel-Crafts, Friedlander,
Grignard, Fukuyama, Heck, Knoevnagel, Paal-Knorr, Mannich, Michael,
Mukaiyama, Pictet-Spengler, Perkin, Prins, Reformatsky,
Reimer-Tiemann, Robinson, Stork, Strecker, Vilsmeier, Wittig
Wagner-Meerwein. Mitsonobu reaction. 1,3-dipolar cycloaddition in the
construction of rings. Prevost and Woodward procedures.
- Oxidation and reduction chemistry. Metal hydrides as reagents.
Aluminum/boron hydride reagents & hydroboration reaction.
Baeyer-Villiger, Oppenauer, Dess-Martin, Swern, Jones oxidation
reactions. Meerwein-Ponndorf-Verley, Wolff-Kishner, Rosenmund,
Clemmensen reduction reactions.
- Selected reagents in organic synthesis: Barbier and Grignard,
organolithium, organosilicon, organo zinc based organometallic
reactions involving C-C bond formations. Selected functional group
transformations organic synthesis.
- F. A. Carey, R. J. Sundberg, Advanced Organic Chemistry Part A:
Structure and Mechanism & Part B: Reactions and Synthesis, 5th Ed,
Springer, New York (2007).
- R. T. Morrison, R. N. Boyd, Organic Chemistry, Indian Edition,
6th Ed, Pearson Education, New Delhi (2007).
- W. Carruthers, I. Coldham, Modern Methods of Organic Synthesis,
Indian Edition, 4th Ed, Cambridge (2004).
- J. Clayden, N. Greeves, S. Warren, P. Wothers, Organic
Chemistry, Oxford University Press, New York (2006).
- L. G. Wade Jr., M. S. Singh, Organic Chemistry, Indian Edition,
6th Ed, Pearson Education, New Delhi (2008).
- E. L. Eliel, S. H. Wilen, L. N. Mander, Stereochemistry of
Organic Compounds, Wiley, New York (2005).
- T. Laue, A. Plagens, Named Organic Reactions, 2nd Ed, John
Wiley & Sons Inc, Hoboken, New Jersey (2005).
