IDC305: Selected analytical techniques

        [Cr:4, Lc:3, Tt:1, Lb:0]

Course Outline

This course consisting of four major analytical topics as described below is developed for students with interest in interdisciplinary subjects.

• Magnetic Resonance Spectroscopy: Introduction to NMR: Spin and spin angular momentum, CW NMR, pulse NMR, sampling, bandwidth, detection and acquisition of NMR signals, time and frequency domain spectra, FT-NMR, resolution and sensitivity in NMR. Spin interactions in NMR, chemical shift, scalar or J-coupling, dipolar interaction and quadrupole interaction, quantum mechanical description of spin-interactions, spin interactions in the solution and solid-state.

  Introduction to EPR: Zeeman Effect, Spin Relaxation and Bloch Equations, Anisotropy of the hyperfine interactions. Instrumentation: CW and pulsed EPR instrument and experimental techniques. Detection of radicals and paramagnetic metal centers; EPR in Catalysis, Porus Materials, Biology and Medicine.

• Molecular Magnetism: Definitions and Experimental Methods. Instruments for measuring magnetization and susceptibility measurements. Diamagnetism, Paramagnetism, Ferromagnetism and Anti-ferromagnetism. Magnetic Anisotropy. Hard and Soft Magnetic materials. 1-D, 2-D and 3-D Magnetic materials. Chiral molecule-based magnets. Magnets for communication and information technology.
• Mass Spectrometry: Types of mass analysers (magnetic, quadrupole, time of flight, etc.), types of detectors (electron multipliers, Faraday cup, microchannel plates, and array transducers), types of ion sources (electron impact ionization, fast atom/ion bombardment (FAB), secondary ion mass (SIM), thermal ionization, laser ionization, matrix-assisted laser desorption and science (for example, ultra-trace analysis, isotope ratio measurements, and surface characterization).
• Thermal Analysis and Microscopy Techniques: For characterization of materials, Biomaterials, and Pharmaceutical Products. Principles and applications of various thermal analysis techniques, such as Thermogravimetric analysis (TGA), Differential Scanning Calorimetry (DSC), Differential Thermal Analysis (DTA), Dynamic Mechanical Analysis (DMA), Thermomechanical Analysis (TMA). Principles and applications of spectroscopic techniques for surface analysis, such as Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM).

Recommended Reading

• M. H. Levitt, Spin dynamics: Basics of Nuclear Magnetic Resonance, 2nd edition, John Wiley & Sons, England (2008).
• R. S. Macomber, A Complete introduction to modern NMR techniques, 1st edition, John Wiley & Sons, England (1998).
• J. A. Weil and J. A. Bolton, Electron Paramagnetic Resonance: Elementary theory and Practical Applications, 2nd edition, Wiley Interscience (2007).
• E. de Hoffmann and V. Stroobant, Mass Spectrometry: Principles and Applications, 3rd edition, Wiley Interscience (2007).
• M. Getzlaff, Fundamentals of Magnetism, 1st edition, Springer (2007).
• M. E. Brown, Introduction to Thermal Analysis: Techniques and Applications, Springer, 2nd edition (2001).
• L. Que (ed.), Physical Methods in Bioinorganic Chemistry: Spectroscopy and Magnetism, University Science Books (2000).