Subsections
[Cr:3, Lc:2, Tt:1, Lb:0]
- Cell division: Cell division in bacteria and eukaryotes. Discovery of
chromosomes. Mitosis and cytokinesis. Cell cycle control.
- Meiosis: Meiosis produces haploid cells from diploid cells. Discovery
of reductional division. Features of meiosis: synapsis, homologous
recombination, reductional division. Chromosomal basis of inheritance
- The transplantation experiments. The Griffith experiments. The
Avery-Chase experiments. The structure of DNA. DNA replication. The
Meselson-Stahl experiment. The replication process. Eukaryotic DNA
replication.
- The central dogma in biology: The genetic code. Discovery of the
genetic code. Organization of prokaryotic and eukaryotic genes and
chromosomes. Transcription. Translation. Differences between
prokaryotic and eukaryotic gene expression.
- Control of Gene expression: Transcriptional regulation in bacteria.
The operon. Repressors, promoters and activators. Transcriptional
regulation in eukaryotes. Effect of chromosome structure.
Post-transcriptional control in eukaryotes.
- Cellular mechanisms of Development: Overview of development. Vertebrate development,Insect development, Plant development. Multicellular organisms employ the same mechanism of development. A comparison of axis specification in plants and animals. Cell movement and induction (taking examples from plant and animal).Determination. Pattern formation. Expression of homeotic genes. ABC model of flower development and early events in plant embryo development Programmed cell death
- Gene Technology. Recombinant DNA technology. Restriction endoncleases.
Gene cloning, techniques, Plasmids, Vectors, Expression vectors,
cloning vectors, cDNA libraries, genomic libraries, DNA sequencing,
PCR.
- Genomics: Genome sequencing projects. The history of the human genome
sequencing project. Strategies for genome sequencing. Uses and
challenges in genomics.
- D. Sadava, W. K. Purves, G. H. Orians, and H. C. Heller, Life:
the science of biology, 8th Edn., Sinauer Assoc. & Freeman & Co.
(2008).
- N. A. Campbell, J. B. Reece, R. B. Jackson, M. L. Cain, L. A. Urry, S.
A. Wasserman, P. V. Minorsky, Biology, 8th Edn.
Benjamin-Cummings Pub Co. (2007).
