Subsections
[Cr:4, Lc:3, Tt:0, Lb:0]
Knowledge of the content of CHM302 is essential to follow this course.
- Recent advances in selected metal-mediated coupling reactions and
mechanisms: Buchwald-Hartwig, Suzuki, Sonogashira, Fukuyama, Heck,
Tsuji-Trost, Hiyama, Kumada, Negishi, and Stille coupling reactions.
Selected familiar named reactions and their recent advances with their
mechanistic aspects.
- Reaction mechanisms, functional group transformation in synthetic
organic chemistry and its importance.
- Selected transition metal-based catalytic reactions in modern organic
synthesis. Selected important reagents in modern organic synthesis.
Alpha-diazo ketones and their synthetic reactions for C-C bond
formation.
- Recent trends in organometallic reactions involving C-C bond
formations: Magnesium, Zinc, Indium-mediated stereoselective additions
to carbonyl compounds.
- Lewis acids and Lewis acid-catalyzed reactions and their importance in
modern organic synthesis.
- Stereo-, chemo-, and regio-selective reactions: Hydrogenation and
addition to multiple bonds and elimination reactions and mechanisms.
- Protective groups and their importance in synthetic organic chemistry.
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4th Ed, Cambridge (2004).
- F. A. Carey, R. J. Sundberg, Advanced Organic Chemistry Part A:
Structure and Mechanism & Part B: Reactions and Synthesis, 5th Ed,
Springer, New York (2007).
- K. C. Nicolaou, T. Montagnon, Molecules That Changed The World,
1st Ed, Wiley-VCH, Weinheim, Germanyx, (2008).
- R. Mahrwald, Modern Aldol Reactions, Volumes 1 & 2, Wiley-VCH,
Weinheim (2004).
- A. de Meijere, F. Diederich, Metal-Catalyzed Cross-Coupling
Reactions, 2nd Ed, Wiley-VCH Verlag GmbH, Weinheim (2004).
- P. G. M. Wuts, T. W. Greene, Greene's Protective Groups in
Organic Synthesis, 4th Ed, John Wiley & Sons, Inc. (2006).
- M. Nògrádi, Stereoselective Synthesis, VCH Verlagsgesellschaft
GmbH, (2007).
- T. Laue, A. Plagens, Named Organic Reactions, 2nd Ed, John
Wiley & Sons, Hoboken, New Jersey (2005).
