Subsections
[Cr:4, Lc:3, Tt:0, Lb:0]
- Prologue and a historical perspective.
- Review of thermodynamic principles relevant to biochemistry:
Laws of thermodynamics. Free energy. Chemical equilibrium.
- Structural aspects of biomolecules:
- Amino acids and proteins.
Covalent structures of proteins. Protein 3-dimensional structures. Domains and Motifs. Protein structure-function
mechanisms. Overview of protein families and superfamilies. A case study
on Hemoglobin.
- Nucleic acids and their structure.
- Sugars and polysaccharides.
- Lipids and membranes.
- Enzymes and their mechanisms of action: Introduction to enzymes.
Rates of enzymatic reactions. Enzymatic catalytic mechanisms: lysozyme
and serine proteases.
- Metabolism: Carbohydrate metabolism. Electron transport and oxidative phosphorylation.
Photosynthesis. Lipid metabolism. Amino acid metabolism. Nucleotide metabolism.
Integration of metabolic pathways and metabolic disorders.
- Voet and Voet, Biochemistry 4th Edn. Wiley (2011).
- Lehninger, Principles of Biochemistry 5th Edn. Freeman (2009).
